本硕授课课程: 讲授本科生课程: 普通生物学技术,生物信息学,食品检验与分析,高级生物化学及生物化学实验等。 科研项目: 1. 山东省自然科学基金青年基金项目,ZR2021QC193,新型异亮氨酸-4羟化酶的立体选择性机制及其分子改造研究,2022-01-01至2024-12-31,15万元, 在研,主持。 2. 国家自然科学基金委员会, 面上项目, 31771911, 维生素D3前体生物合成关键酶胆固醇7-脱氢酶系的构效研究, 2018-01-01 至 2021-12-31, 60万元, 在研, 参与。 3. 生物基材料与绿色造纸国家重点实验室主任基金,ZZ20200131,碱性木聚糖酶高效异源表达及耐碱性分子改造研究,2020-10至2022-10,2万元,已结题,主持。 4. 生物基材料与绿色造纸国家重点实验室开放基金,高活性耐高温甘露聚糖酶的高效表达与特异性改造研究,KF201921,2020-01至2021-12,7万元,已结题,主要参与人。 主要论文: 1. D. Sun, C. Li, P. Cui, J. Zhang, Y. Zhou, M. Wu, X. Li, T-F. Wang, Z. Zeng, H-M. Qin, Reshaping the binding channel of a novel GH113 family β-mannanase from Paenibacillus cineris (PcMan113) for enhanced activity, Bioresour Bioprocess 2022, 9,17. 2. D. Sun, J. Zhang, C. Li, T-F. Wang, H-M. Qin, Biochemical and structural characterization of a novel thermophilic and acidophilic β-mannanase from Aspergillus calidoustus, Enzyme Microb Tech 2021,150, 109891. 3. D. Sun, X. Chen, C. Zhu, Physicochemical properties and antioxidant activity of pectin from hawthorn wine pomace: A comparison of different extraction methods, Int J Biol Macromol 2020, 158: 1239-1247. 4. D. Sun, X. Liu, M. Zhu, Y. Chen, C. Li, X. Cheng, Z. Zhu, F. Lu, H.-M. Qin, Efficient biosynthesis of high-value succinic acid and 5-hydroxyleucine using a multienzyme cascade and whole-cell catalysis, J. Agric. Food Chem 2019, 67(45): 12502-12510. 5. D. Sun, D. Gao, X. Liu, M. Zhu, C. Li, Z. Zhu, F. Lu, H.-M. Qin, Redesign and engineering of a dioxygenase targeting biocatalytic synthesis of 5-hydroxyl leucine, Catal Sci Technol 2019, 9, 1825-1834. 6. D. Sun, D. Gao, P. Xu, Q. Guo, Z. Zhu, X. Cheng, S. Bai, H.-M. Qin, F. Lu, A novel l-leucine 5-hydroxylase from Nostoc piscinale unravels unexpected sulfoxidation activity toward l-methionine, Protein Expr Purif 2018,149, 1-6. 7. D. Sun, X. Cheng, D Gao, P. Xu, Q. Guo, Z. Zhu, M. Zhu, X. Wang, H.-M. Qin, F. Lu, Properties, biosynthesis, and catalytic mechanisms of hydroxyl-amino-acids, IOP Conf. Series: Earth and Environmental Science 188 (2018) 012084. (EI) 8. D. Sun, Q. Guo, Z. Zhu, S. Li, J.-W. Wang, Y.-F. Zhang, L. Guan, H.-M. Qin, F. Lu, Research progress of squalene synthase on function and application, Lecture Notes in Electrical Engineering, vol 444 (2017). (EI) 9. D. Sun, Z. Zhou, C. Zhu, Y. Sun. Effects of culture medium on PUFAs production by Mortierella isabellinas, Lecture Notes in Electrical Engineering, vol 333 (2015). (EI) 10. 孙登岳,程晓涛,郭倩倩,许盼盼,朱张亮,秦慧民,路福平,疏水性氨基酸的羟基化研究进展,生物工程学报. 2018, 34(7): 1046-1056. 11. 朱梦露,王雪雨,刘鑫,路福平,孙登岳(通讯),秦慧民,亮氨酸5-羟化酶的生化及结构特征分析,中国生物工程杂志. 2019, 39(12): 24-34. |